British Air Force Typhoon FGR4s have conducted a mission with French warplanes in a combined operation against an subterranean weapons facility in Syrian territory operated by the IS group, according to the UK's MoD.
The site, located using surveillance, was believed to be housing weapons and explosive materials, the release indicated, and was positioned in hills just north of the historic site of Palmyra in central Syria.
"Our aircraft employed Paveway IV guided bombs to target a several approach shafts leading to the facility... initial indications indicate the target was engaged successfully," the MoD said.
There was no sign of any civilian impact in the attack on Saturday evening and all the aircraft returned to base without incident, the ministry further stated.
The Typhoon fighters were backed up by a Voyager tanker plane.
IS - also known as Daesh - enforced jihadist rule over large swathes of both Syria and Iraq prior to its 2019 collapse.
"This action shows British leadership, and resolve to work closely with our allies, to stamp out any re-emergence of IS and their dangerous and violent ideologies in the Middle East," Britain's Defence Chief John Healey remarked.
UK warplanes have performed surveillance missions over Syria to "prevent any efforts to regroup" of the group following its military defeat at the battle of Baghuz in 2019, the ministry said.
"I must thank all the members of our armed forces participating in this operation for their expertise and their valour," he added. "They were part of a great many British troops on duty over the festive period. This mission, to take out dangerous terrorists who pose a risk to our safety, highlights how our armed forces are always on standby, all year round, ensuring Britain's security domestically and powerful internationally."
In December, the US military carried out what it termed a "massive strike" on Islamic State objectives in Syria, following an assault claimed the lives of two US servicemembers and a local interpreter in the Palmyra area.
The UN estimates Islamic State still boasts between 5,000 and 7,000 combatants in both countries.
